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The diagnosis of leptomeningeal gliomatosis is discussed in relation to a single case studied in detail.Histology showed extensive subarachnoid spread of tumour that seemed to originate in an astrocytoma of the ventricular wall.The spinal fluid was zanthochromic with a high protein content.Reports of primary leptomeningeal gliomatosis are reviewed and the need for detailed histological study of the brain in such cases is emphasised. |
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